Tetracycline

Appearance: Light yellow to yellow crystalline powder. Melting point 181-182 ℃ (decomposition).Solubility: soluble in alkaline solution, with a reference solubility of 10mg/ml in 1M NaOH, slightly soluble in ethanol, and extremely slightly soluble in water. Stable in air, darkens in sunlight, and is easily destroyed in alkaline solutions. Purpose: Biochemical research, it is a broad-spectrum antibiotic extracted from the culture medium of Streptomyces rhamnosus. Its antibacterial spectrum, antibacterial effect, and uses are basically the same as tetracycline and streptomycin. Tetracycline is an antibiotic synthesized by catalytic dehalogenation of streptomycin. It has low toxicity and is a broad-spectrum antibacterial agent, with bactericidal effects at high concentrations. In addition to common Gram positive bacteria, Gram negative bacteria, and anaerobic bacteria, most species of rickettsia, mycoplasma, chlamydia, atypical mycobacteria, and spirochetes are also sensitive to this product. This product has a better effect on Gram positive bacteria than Gram negative bacteria, but Enterococcus is resistant to it.Tetracycline can be used to treat chronic inflammatory cells. Tetracycline derivatives can also induce apoptosis in cells such as osteoclasts, T lymphocytes, as well as in artificially cultivated monocytes and macrophages. Used for cell experiments, after dissolution, it needs to be filtered and sterilized using a disposable needle filter.