[Des-Asp1]-Angiotensin I, Human

Angiotensin I (1-9) is found in vivo and accumulates in animals treated with ACE inhibitors. It has been shown that the nonapeptide may be generated in heart and kidney by endothelium-associated ACE2. Kramkowski et al. observed that DRVYIHPFH generated from Ang I in platelets enhances thrombosis in rats.